Browsing by Subject "A61K 38/00"

Now showing items 1-20 of 38

    • Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby 
      Hook, Magnus; Xu, Yi; Sillanpaa, Jouko V.; Sthanam, Narayana; Ponnuraj, Karthe; Patti, Joseph M.; Hutchins, Jeff T.; Hall, Andrea; Bowden, Maria G. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2009-11-10)
      A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus and Bacillus bacteria, which can ...
    • Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby 
      Hook, Magnus; Xu, Yi; Sillanpaa, Jouko V.; Sthanam, Narayana; Ponnuraj, Karthe; Patti, Joseph M.; Hutchins, Jeff T.; Hall, Andrea; Bowden, Maria G. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2010-12-14)
      A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus and Bacillus bacteria, which can ...
    • Collagen binding protein compositions and methods of use 
      Hook, Magnus; Patti, Joseph M.; House-Pompeo, Karen; Sthanam, Narayana; Symersky, Jindrich (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2001-09-11)
      Disclosed are the cna gene and cna-derived nucleic acid segments from Staphylococcus aureus, and DNA segments encoding cna from related bacteria. Also disclosed are Col binding protein (CBP) compositions and methods of ...
    • Crystal structure of Staphylococcus aureus clumping factor A in complex with fibrinogen derived peptide and uses thereof 
      Hook, Magnus; Ko, Ya-ping; Smeds, Emanuel; Ganesh, Vannakambadi K. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2012-10-02)
      The present invention provides a method for determining the structure of a microbial surface components recognizing adhesive matrix molecule in complex with fibrinogen, by providing a ClfA complexed with a fibrinogen ...
    • Crystal structure of Staphylococcus aureus clumping factor A in complex with fibrinogen derived peptide and uses thereof 
      Hook, Magnus; Ko, Ya-Ping; Smeds, Emanuel; Ganesh, Vannakambadi K. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2021-06-22)
      The present invention discloses crystal structure of Staphylococcus aureus Clumping factor A (ClfA) in complex with fibrinogen (Fg) derived peptide. Also, the present invention also discloses the use of this structure in ...
    • DbpA compositions 
      Guo, Betty P.; Hook, Magnus (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2001-04-10)
      Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
    • DbpA compositions and methods of use 
      Guo, Betty P.; Hook, Magnus (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2001-11-06)
      Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
    • Decorin binding protein compositions 
      Guo, Betty; Hook, Magnus (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2001-05-08)
      Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
    • Decorin binding protein compositions and methods of use 
      Guo, Betty P.; Hook, Magnus (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2001-06-19)
      Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
    • Decorin binding protein compositions and methods of use 
      Guo, Betty; Hook, Magnus (United States. Patent and Trademark Office; Texas A&M University. Libraries, 1998-12-29)
      Disclosed are the dbp gene and dbp-derived nucleic acid segments from Borrelia burgdorferi, the etiological agent of Lyme disease, and DNA segments encoding dbp from related borrelias. Also disclosed are decorin binding ...
    • Discovery of the first selective C5A receptor 2 (C5L2/C5AR2) ligands 
      Monikis, Dmitrios; Floudas, Christodoulos; Woodruff, Trent; Cooper, Matthew A.; Croker, Daniel E.; Monk, Peter, N. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2019-05-07)
      A method of selectively modulating the activity of C5a receptor 2 (C5aR2). The method includes exposing the receptor to a compound that selectively modulates C5aR2 compared to C5a receptor 1 (C5aR1). In some cases, the ...
    • Extracellular matrix-binding proteins from Staphylococcus aureus 
      Patti, Joseph M.; Foster, Timothy J.; Josefsson, Elisabet; Eidhin, Deidre Ni; Hook, Magnus A. O.; Perkins, Samuel E. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2008-06-03)
      Isolated extracellular matrix-binding proteins, designated ClfB, SdrC, SdrD and SdrE, and their corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or ...
    • Extracellular matrix-binding proteins from staphylococcus aureus 
      Patti, Joseph M.; Foster, Timothy J.; Josefsson, Elisabet; Eidhin, Deidre Ni; Hook, Magnus A. O.; Perkins, Samuel E. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2004-01-20)
      Isolated extracellular matrix-binding proteins, designated ClfB, SdrC, SdrD and SdrE, and their corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or ...
    • Feline CD86 polypeptides and nucleic acids 
      Cochran, Mark D.; Collisson, Ellen W.; Choi, In-soo; Winslow, Barbara J.; Cochran, Mark D. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2011-12-06)
      The present invention provides isolated and purified DNA encoding feline CD80 (B7-1) ligand, feline CD86 (B7-2) ligand, feline CD28 receptor, or feline CTLA-4 (CD152) receptor, as well as vectors comprising nucleic acid ...
    • Feline CTLA-4 nucleic acid and polypeptides 
      Collisson, Ellen W.; Choi, Insoo; Winslow, Barbara J.; Cochran, Mark D. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2010-06-29)
      The present invention provides isolated and purified DNA encoding feline CD80 (B7-1) ligand, feline CD86 (B7-2) ligand, feline CD28 receptor, or feline CTLA-4 (CD152) receptor, as well as vectors comprising nucleic acid ...
    • FGF-affinity chromatography 
      Mckeehan, Wallace L.; Luo, Yongde (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2004-11-02)
      The present invention relates to a method and apparatus for isolating anticoagulant heparin or heparan sulfate by binding the anticoagulant heparin or anticoagulant heparan sulfate onto an affinity matrix and separating ...
    • Fibronectin binding protein compositions and methods of use 
      Hook,Magnus; Patti, Joseph M.; House-Pompeo, Karen L.; Speziale, Pietro; Joh, Danny; Mcgavin, Martin J. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2004-02-03)
      Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
    • Fibronectin binding protein compositions and methods of use 
      Hook, Magnus; Patti, Joseph M.; House-pompeo, Karen L.; Speziale, Pietro; Joh, Danny; Mcgavin, Martin J. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2006-10-31)
      Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
    • Fusion Proteins (Seldegs) For Selectively Depleting Antigen-specific Antibodies And Methods Of Use Thereof 
      Ober, Elizabeth Sally Ward; Devanboyina, Venkata Siva Charan; Ober, Raimund Johannes (United States. Patent and Trademark Office; Texas A&M University. Libraries, 10/4/2022)
      The present disclosure includes a fusion protein, called a "Seldeg", including a targeting component that specifically binds to a cell surface receptor or other cell surface molecule at near-neutral pH, and an antigen ...
    • HSP20 inhibits amyloidogenesis and neurotoxicity 
      Ficht, Allison; Good, Theresa; Carson, Ken; Lee, Sundmun (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2014-04-29)
      The present invention compositions and methods of using at least a portions of an isolated and purified α-crystallin polypeptide that includes one or more β-pleated sheets and that prevents neurotoxicity and amyloidogenesis.